A nonprofit organization called the Fermi Explorer Mission announced today that it intends to launch a spacecraft to our nearest star system by the end of 2029. 

It’s a hugely ambitious mission—if all goes well, the spacecraft could take up to 80,000 years to arrive at Alpha Centauri, which is 4.4 light-years away. And the spacecraft will follow a novel trajectory discovered by an AI system developed by Physical Superintelligence (PSI), an AI physics research lab. PSI is launching today with $58 million in funding led by Breakthrough Energy, a climate-focused investment group founded by Microsoft cofounder Bill Gates.

It’s not the first time this has been tried. In 2016, the billionaire tech investor Yuri Milner announced an interstellar mission called Breakthrough Starshot to launch humanity’s first spacecraft to Alpha Centauri. The plan was to use powerful lasers that would propel tiny probes to a fifth of the speed of light—fast enough to reach Alpha Centauri within 20 years. Milner pledged $100 million toward a proof of concept. But a decade later, nothing has launched.

“We didn’t want to do another Breakthrough Starshot,” says Philip Johnston, the cofounder and president of the Fermi Explorer Mission. “We’re dead set on something actually launching.” The new mission, currently funded by individual private donors, is expected to cost just $15 million. 

To stick to that budget, “we are not constraining ourselves to doing it in a human lifetime,” says Johnston. “Let’s just figure out the way to get to another star.” 

The spacecraft will carry cargo weighing at least one kilogram. That will include artistic and scientific payloads, messages, and a copy of the Golden Record, a gold-plated disc of Earth’s sounds and images that NASA attached to its two Voyager probes in 1977 as a message to any civilization that might find them.

Engineering an interstellar journey is extremely difficult. Alpha Centauri is about 25 trillion miles away from Earth. One of the fastest objects that humans have ever launched, the Voyager 1 probe, has been flying since 1977 and has covered less than 1% percent of that distance. At its speed, the trip would take more than 70,000 years.

Johnston and his team spent a year trying, and failing, to find a way for a small, solar-powered spacecraft costing only $15 million to reach Alpha Centauri. They kept running into the knotty problem of how to give the spacecraft enough power without making it too heavy (and thus more fuel-guzzling). 

After the Fermi team struggled to find a workable route, Johnston mentioned the problem in a podcast hosted by Alex Wissner-Gross, a physicist who cofounded PSI. Wissner-Gross offered to run it through an AI system the lab developed, called Get Physics Done. It’s open-source software that takes a physics research question, breaks it into smaller tasks, and decides which simulations to run, using AI models including Anthropic’s Claude or OpenAI’s GPT.

A week later, the AI system turned up a novel trajectory, to Johnston’s surprise. It combined well-known orbital maneuvers in a way the Fermi team had not considered, according to a paper that has not been peer-reviewed. It suggested that the spacecraft could first slow down so its orbit swings in close to the sun—closer than Mercury. On each close pass, it would fire its engine so that the solar panels get four times the light, and a burst of thrust delivered at high speed would buy more energy than the same burst anywhere else. Because the engine would run only near the sun, the solar panels could stay small and the spacecraft light.

The system conducted the research mostly on its own for three days, running on a billion tokens, says Matt Pines, the cofounder and CEO of PSI. An astrophysicist on PSI’s staff steered it to follow the mission’s requirements, asked for a cost analysis and clearer charts, and checked the output for errors.

“The fact that it came up with an entirely different mission profile, one that was creative and not one [the Fermi team] had considered—that was the more surprising aspect,” says Pines. Still, the model lacks a human researcher’s judgment and taste, he says. It has no reliable sense of which problems are interesting or which approaches are worth pursuing, so it often gets stuck chasing dead ends or failing to explore different approaches. “I don’t think we’ve yet figured out how these models can internally represent something like that,” he says of research judgment.

Even if the Fermi probe launches, “we’re pretty confident that we will not be the first to arrive” at Alpha Centauri, says Johnston, since he expects spacecraft technology to improve. If an engine a thousand years from now is even 20% faster than today’s, a spacecraft launched then would still beat Fermi’s probe to Alpha Centauri by more than 10,000 years. 

But the Fermi project isn’t just an interstellar mission driven by engineering ambition. It’s also a quest to answer one of the oldest open questions in physics. In 1950, the physicist Enrico Fermi posed a puzzle: The galaxy has hundreds of billions of stars, most of them far older than our sun. Even a civilization traveling slowly between stars could spread across the whole galaxy in a few million years, which pales in comparison to how old the galaxy is. If there is intelligent life somewhere, we should have seen signs of its existence by now.

That means either reaching for another star is too difficult or other intelligent species simply haven’t bothered. But once the Fermi probe launches, we will become a civilization that can and wants to reach another star, meaning that neither explanation might be what’s keeping the galaxy unexplored. That could point us toward more unsettling possibilities, says Johnston. Maybe life like ours is almost unimaginably rare. Or maybe intelligent life is common but tends to die out before it can spread. 

If the latter is true, “one of those reasons could be that once you hit superintelligence, that for some reason is self-destructive,” says Johnston. “Maybe in the next 50 years, there’s some great filter that we do not pass through. That all intelligent civilizations, for some reason, do not pass through.”

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For years, legacy technology has been a problem companies knew they needed to solve, but one they often struggled to tackle. The cost, complexity, and risk of replacing business-critical systems could make modernization feel like a disruption to manage instead of an opportunity to pursue. But with the rise in customer expectations and the changes AI brought to the economics of software development, that calculation is changing. Bupa’s modernization of its My Bupa mobile application offers a case study in what becomes possible when a legacy migration is treated as a business transformation rather than a technology rewrite.

Bupa CIO of health insurance Asifa Sherazi describes the risks of waiting for legacy systems to become an emergency: “The end-of-life technology is a risk that compounds quietly, and then arrives all at once.” For Bupa, moving its application from Xamarin to native Swift and Kotlin improved the app rating from 3.7 to 4.7, while the user-perceived crash rate fell by nearly 24 percentage points on Android and eight points on iOS. “What they’ll notice is that when they need us, often at a stressful moment, it just simply works,” Sherazi says.

Sanjeev Tripathi, senior vice president and region head of BFSI, healthcare, and public sector for Australia, New Zealand, and Southeast Asia at Infosys, contends that AI is helping change the equation. “The emergence of AI is fundamentally shifting the economics of modernization,” he says, reducing the effort, risk, and time traditionally associated with these programs. At Bupa, combining AI-assisted reverse engineering with forward engineering helped deliver the transformation in approximately 60% less time than would have been possible in the pre-AI era.

Sherazi and Tripathi also highlight the human dimension of modernization: preserving institutional knowledge, giving teams capacity to adapt, and creating an environment where employees can surface problems early.

Looking ahead, both experts see modernized platforms as foundations for more personalized, predictive and AI-driven experiences. The payoff of modernization may be less about replacing aging technology and more about building the flexibility needed for whatever comes next. 

“Modern platforms will become the base for far more intelligent AI-driven ecosystems, where AI is not just an add-on, but it is built into everything from design to operations. That’s how the modern platforms will evolve, and the customer experiences will become far more personalized and predictive,” says Tripathi. For Sherazi, that shift is already changing the questions organizations can ask: “It used to be, can our platform support that? Now, it’s: is that the right thing to do for our customers?”

This episode of Business Lab is produced in partnership with Infosys.

Full Transcript:

Megan Tatum: From MIT Technology Review, I’m Megan Tatum, and this is Business Lab, the show that helps business leaders make sense of new technologies coming out of the lab and into the marketplace.

Our topic today is legacy modernization. Companies across industries continue to struggle to bring AI modernization to legacy technology stacks, increasing the risk of losing vendor support, degraded customer experience, and limited capacity for innovation.

Two words for you: future-ready foundation.

My guests are Asifa Sherazi, who is CIO of health insurance at Bupa, and Sanjeev Tripathi, who is senior vice president, region head of BFSI, healthcare, and public sector for Australia, New Zealand, and Southeast Asia at Infosys.

This podcast is produced in association with Infosys.

Welcome, Asifa and Sanjeev.

Asifa Sherazi: Thank you, Megan. Delighted to be here.

Sanjeev Tripathi: Thanks, Megan. Wonderful to be here. And good talking to you again, Asifa.

Megan: Thank you both so much for being here. Asifa, if I could start with you just to set the context for our conversation. There are seven million healthcare customers across the Asia-Pacific. Could you tell us a bit more about Bupa and the challenges it’s faced in its modernization plan?

Asifa: Yes, absolutely. Let me start with something about Bupa that shapes everything we do. We are a global healthcare organization. Think hospitals, clinics, dental, age care, digital health, alongside our insurance business. We reinvest back into the organization, so into our services, our capability, our teams, and our outcomes that we deliver for our customers. In Asia-Pacific, we serve around, as you said, seven million customers across health insurance and health services, individuals, families, corporate clients, patients. Our purpose, helping people live longer, healthier, happier lives is more than just a statement. It actually shapes our strategy, guides our investment decisions, and influences the choices our teams make every day.

Now, for most of our health insurance members, the day-to-day digital relationship with Bupa begins through My Bupa, our self-service platform. It’s the front door for managing cover, updating policy details, submitting claims, checking entitlements. Alongside of it, Blua plays a complimentary role. Where My Bupa helps members manage their cover, Blua helps them manage their health, digital healthcare services, clinical support, preventative health. And together, they let us move beyond transactional interactions towards more personalized, proactive care.

Here was our challenge. Our mobile app, My Bupa, was built on Xamarin, and Microsoft support for it ended sometime in 2024. We had extended support in place, so our customers remained protected throughout, but we were clear-eyed that this was a bridge, not a destination. The runway was finite, and it was shortening for us. We made the decision to modernize from a position of stability proactively for the long-term safety and experiences of our customer rather than waiting until circumstances forced our hand, because the platform carrying our most important customer relationship was in effect standing still while the world around it was moving.

Megan: Right. So you decided to act really proactively in that sense. And so, Asifa, what are some of the risks then of sticking with end-of-life technologies, and how will moving away from legacy technologies help you improve the customer experience?

Asifa: Yeah. Look, the end-of-life technology is a risk that compounds quietly, and then arrives all at once. We saw it in three ways. The first is security and compliance. Once a technology is out of vendor support, the flow of security updates and fixes changes fundamentally. In our case, we put extended support in place as a bridge so our customers stayed protected. But extended support buys you time, it doesn’t buy you a future. In healthcare, we hold some of the most sensitive information a person will ever share with an organization. That isn’t data to us, it’s trust. And trust is extraordinarily expensive to rebuild. We weren’t prepared to run that risk on a shortening runway.

The second is losing control of your own roadmap. How I’d explain that is iOS and Android don’t stand still. Every operating system release, every change to app store requirements becomes something that you react to rather than plan for. As each one slows you down a little further, over time, that opens a widening gap between what customers expect and what you can actually give them. We’re all customers. We don’t benchmark a health insurer against other health insurers. We benchmark against whatever app we used last.

And the third way was, and this is one red flag for peers, is the shrinking talent pool. Xamarin is legacy technology, and the engineering expertise available for it is limited. You end up with a critical customer platform supported by a narrowing group of specialists. That’s a workforce risk wearing a technology costume. We partnered with Infosys and we migrated the entire application estate from Xamarin to fully native Swift and Kotlin, and the customer outcomes are why we’re comfortable talking about this today. Our app rating moved from 3.7 to 4.7. Some of the stats that I’d love to share are that the user-perceived crash rate fell by nearly 24 percentage points on Android and eight points on iOS. The Android login success per visit doubled back up to 77%, and that’s one the team that is most proud of, because a login failure isn’t a technical event. It’s a person who wanted to check their cover and they couldn’t.

The team achieved 100% feature parity in a single release, and 90% of our active customer base moved to a new version, and they’ve, I think, downloaded nearly 1.8 million unique downloads. From our customers’ perspective, customers will never think about any of this as a technology change, and they shouldn’t have to either. What they’ll notice is that when they need us, often at a stressful moment, it just simply works, and that’s the outcome we were really after.

Megan: Those are some really striking results and statistics that you’ve shared there on the success of the migration. I mean, Sanjeev, could you talk a bit about why modernizing legacy technologies is so critical at this time, and how Infosys has approached that transformation journey with Bupa?

Sanjeev: Sure, Megan. To be honest, legacy modernization initiatives are not new, and there has always been a strong desire to drive modernization across the entire technology landscape. And Asifa covered all the points that I was going to cover about the risks that have been there. But I’ll reiterate, the reality is the industry has been held back by the cost complexity, and also the risks that have been associated with any legacy modernization initiative that has been undertaken historically.

As Asifa mentioned, customer expectations of what was acceptable five, 10 years back are simply not acceptable anymore. The customers today expect a seamless, intuitive, responsive interaction across every channel. And Asifa also covered the growing challenges around security, resilience, talent availability, and so on. Finding talent on legacy technology is extremely, extremely difficult, and that introduces risk in every organization and in every legacy platform, most of which are actually business-critical platforms as well. Security vulnerabilities are getting increasingly difficult to manage, and as I mentioned, finding deep expertise in older technologies is very, very difficult now.

So what has changed? What has changed is that we now have new tools that are available to us to address these challenges. The emergence of AI is fundamentally shifting the economics of modernization, and it’s doing that by helping organizations to reduce the effort, risk, and also the time that is traditionally taken for programs like these, and that is why we believe that the time is now for legacy modernization. In fact, in Infosys, we have six strategic value pools that we have identified in our AI-first value framework, which is publicly available, and legacy modernization is one of these six value pools. And in the market, we are seeing very strong interest across our client base, and they recognize that the opportunity to unlock both technical and business value is now.

With Bupa in particular, we approached the journey as a business transformation rather than simply a technology rewrite, and our approach had two key phases. One is reverse engineering, and then forward engineering. Let me just quickly cover what these two are.

Reverse engineering, what we did is we extracted and we understood the rules, the processes, and the logic within the legacy environment, and that’s a standard approach we took, we take in any legacy modernization program. What that does is it allows us to preserve the critical business functionality, but at the same time, it avoids the risks that often come with large-scale migration programs.

The second aspect is forward engineering, where we re-architected the solution to enable a reimagined customer experience. The objective is not just a feature-by-feature migration or ensuring feature parity, which is important, but it is even more important that since we’re investing this kind of money to create a modern platform that is scalable, maintainable, and is also capable for future innovation, and that’s what Asifa mentioned about you need to be in control of your own roadmap. You have to build a platform which is capable of supporting future innovation as well. We essentially ensured nothing was lost in translation, and we significantly improved the platform stability and long-term maintainability. And some of the metrics that Asifa mentioned reflects the meaningful improvement in customer experience as well.

Finally, just one more point before I close this question is the time to market. I spoke about the time is now, and because we’ve got the power of the tools that are available now. What AI allowed us is to accelerate the transformation dramatically. What would have traditionally been a long and complex modernization, was delivered in approximately 60% less time than what would have happened in pre-AI era, and that is the real story.

Megan: So AI in this context is a real enabler in terms of the economics and the speed and all of those things you’re talking about. If I could come back to you, Asifa, as much as modernization is a technology challenge, there is the human component as well, and I wondered if you could talk about how you prepared employees for these new technologies, and what challenges and solutions you faced on that front as well?

Asifa: The human side of it is what I’m really passionate about. Technology was only half the challenge. The real work was helping people move from what they knew to what was possible. Modernization isn’t just about replacing systems, it’s about giving teams the confidence, the capability, the clarity to embrace a different future, and that’s what determines whether change actually succeeds.

From that experience, there were three human challenges that stood out for us. The first one was scarcity of expertise on both sides of the transition, and like we said before, Xamarin is a legacy app. We were moving away from a legacy technology, supported by a rapidly shrinking specialist talent pool, and modernizing onto two native platforms. Documentation of that existing environment was limited. Much of the operational knowledge sat in individual experience and in the code base itself, and that created a real dependency on a small number of people. And for the team, it was a confronting reality and a powerful reminder that modernization isn’t just about technology imperative, it’s actually a resilience one.

What changed the dynamic was using AI to do the archeology. As Sanjeev mentioned, Infosys applied AI-assisted reverse engineering to harvest the legacy Xamarin code and extract the flows, the rules, the business logic, and generate native-ready user stories and acceptance criteria from it. The team did a lot of work. They mapped hundreds, I think nearly 1,500 regression scenarios to native epics, and that way, parity critical journeys were preserved by design rather than by memory. The human effect was just as important. Knowledge stopped living with a handful of individuals and became shared across the team, and our people could spend less energy holding institutional memory and more on designing and improving. So that was the first challenge.

The second challenge, Megan, was capacity and not willingness. Our business analysts were fully committed to ongoing feature delivery. And this is a live customer-facing app, and you cannot pause improving the customer experience while you rebuild underneath it. AI-driven discovery and documentation removed almost an estimated of 400 hours of manual BA effort, and that’s not a headcount story, that’s actually people not being asked to do two full-time jobs at once.

The third challenge that stood out was space. Our original internal estimate was around 18 months, and thanks to Sanjeev and the team, almost like a one-team approach of how do we tackle this, the team delivered it in seven, and that’s exhilarating.

t’s also demanding, and both things need saying out loud. We mobilized cross-functional squads across engineering, architecture, testing, release, because managing parallel environments while protecting BAU commitments is such an emotional load as well as a logistical one. We leaned in hard alongside the team, being present rather than reporting from a distance, regular check-ins, genuinely listening to concerns, unblocking things quickly so people weren’t sitting waiting on a decision. And Megan, one thing I’ll say is when you’re compressing 18 months to seven, the most useful thing leadership can do is remove the friction in front of someone else and get out of their way.

But the thing that made the biggest difference was surprisingly simple, actually. We built a visual depiction of the transformation journey, and we updated it every month so the team could actually see how far they’ve come. Because when you deepen migration of this scale, it’s really easy to only see what’s left to be done, and being able to look back at the ground that’s already been covered gave people real intent and real momentum. And genuinely, it was exhilarating to watch. Watching the team’s pride became their fuel.

Megan: I love that idea of it being exhilarating, but exhausting. I think that’s a great description.

Asifa: Yeah. And the leadership lesson for all of us was just simpler than any of it. Programs like this have hard weeks, there’s going to be incidents, delay, difficult conversations. And Sanjeev, you and I have had those conversations many times. The job of leadership in those moments is to absorb the ambiguity rather than transmit anxiety, because if people feel safe telling you bad news early, there’s almost nothing you can’t fix. I say this plainly because it’s the truest thing about the whole program. I am so incredibly proud of this team, because what they achieved in seven months, while continuing to serve customers every single day without disruption, was genuinely remarkable. But what I’m really proud of isn’t the speed and it isn’t the engineering, it’s that the team never lost sight of who it was for, so every decision that we were making, and they came back, it just came back to the person at the other end of the app.

Megan: It sounds like you did an incredible job focusing on that people element just as much as the technology, which is so important. And Sanjeev, we’ve heard some of the incredible results Bupa has had with this, but more broadly, I suppose, looking across modernization use cases, where do you find that companies see the most ROI, and what advice do you have for leaders who need to focus on transformation at that legacy level?

Sanjeev: Thanks, Megan. That’s a very important and actually a very good question, because what we see is modernization ROI is sometimes viewed too narrowly through just a technology lens, and as Asifa mentioned, it is broader than just technology. Legacy modernization has aspects associated with business implications as well, so I’ll just cover that very quickly.

There are two dimensions, as I mentioned. One is technical ROI or technology-related ROI, and second is business ROI. On the technical side, and as you heard from Asifa as well, the biggest benefits come from faster time to market, platform stability and resilience, of course, and a lot of times, in fact, almost in all the cases, lower operating costs, and that is one of the aspects associated with some of the legacy modernization programs.

Besides this, access to broader, more readily available talent pool, and security management, and ensuring that the platforms are secure and free from, as much as possible, free from vulnerabilities in the current environment. At the same time, making it easier to innovate, releases become faster so that the feature delivery into the market becomes faster, and also able to respond to any new technology innovation that comes into play. But this is only on the technology side.

On the business side, however, the returns are often reflected in customer outcomes, and what we typically see are improvements in measures such as net promoter score, and in this case, for example, application ratings that you see on the app store. Both of which are actually very strong indicators of customer satisfaction and digital experience quality. I think it is important for us to cover, look at the ROI from both technology, but more importantly, from a business perspective.

The second part of your question was about what would be my advice to leaders, and I think Asifa covered it very well, where she mentioned that the one-team approach, the providing safe environment to the team to be able to say what is going well, but also what is not going well, and keeping your eye on the end outcome. I think those are very important things. But I would also like to add that don’t treat modernization as a technology initiative. It is a unique opportunity for us to rethink the business platform itself, and rather than pursuing a like-to-like migration, use the investment that you’re making to improve customer experience, simplify processes, and re-architect for capabilities such as real-time personalization and data-driven decision-making. The greatest returns come when technology transformation is directly linked to business outcomes.

And finally, and this is something that I have seen from personal experience multiple times, is you have to think from first principles. AI does not replace good engineering practices. It enables organizations to execute those practices faster, and it enables it faster, but also more consistently and at greater scale. The foundations of good architecture, sound engineering, and clear business objectives will continue to remain important, and in fact, their importance is going to increase as we progress. That, I think, is what I would say anybody embarking on a legacy modernization program should be focused on.

Megan: I love the idea that this is not just about migration. This a chance, as you say, to reimagine what you can deliver and what’s possible. Fantastic. Let’s close with a forward look. Asifa, what innovation are you looking forward to that wouldn’t have been possible before this, and what do you see on the horizon?

Asifa: There’s definitely lots of things on the horizon. But what excites us most isn’t specific technology, it’s that the question in our conversations has changed. It used to be, can our platform support that? Now, it’s is that the right thing to do for our customers? And that’s a profound shift.

There’s three things, Megan, that generally weren’t possible before, and we’ve touched on this a little bit, and Sanjeev’s touched on it as well. This first is speed as a permanent capability. Since launch, Android and iOS, the team has shipped multiple rapid-fire releases, including our migration to a new payment gateway. Bills are now completing four times faster, codes are reaching to testers in about an hour, and we’ve reduced our code base by 30%, and our application footprint’s reduced 18% as well. A simpler estate isn’t an aesthetic preference anymore, it’s what makes the next change cheap, and we’ve bought ourselves optionality to do that.

The second is quality at that speed, which is the part we’ve been most skeptical about five years ago. AI-driven triage and predictive defect analysis, we ran it across nearly 1,400 cases to focus on testing on the highest risk journeys, which meant we went live with zero security defects and zero high severity defects, and Sanjeev mentioned that just before. The old trade-off between moving fast and moving safely is being renegotiated right in front of us, so that’s the second point.

The third one is AI-driven accessibility testing, which the teams treated as a critical rather than an optional opportunity. In healthcare, people who most need to reach us are very often the people whom our poorly designed interface is a genuine barrier, and so being able to test that systematically at scale was a real advance for us as well.

And Megan, you mentioned on the horizon. It’ll be remiss of me not to take the name of agentic AI. The shift from AI that supports a task to AI that completes an outcome end-to-end with proper governance, human oversight at the key decision points. What this program showed us is that the constraint is no longer the models. It’s whether your platforms, data, processes are more than enough to let AI act safely, which is precisely why this work mattered now. Sanjeev alluded to it as well about that underlying architecture. Responsible AI as a source of advantage, not a compliance exercise, I would say. In health, if people don’t trust how you’re using their information, nothing else you build matters. We didn’t modernize to have modern technology. We modernized to earn the right to do the next thing, and to do it in weeks rather than years.

Megan: Absolutely. And now you have those foundations in place, like you say, all of these opportunities open up. Fantastic. And Sanjeev, just finally, as companies complete these migrations, what kinds of innovations and benefits are you seeing, and what do you expect in the next five years?

Sanjeev: Sure. Again, good question, Megan. The reason is there is no uniformity on how these migrations are being done even today. As I mentioned earlier, so where there is simple lift and shift of existing code base onto a new platform, a like-to-like replacement, the benefits generally tend to be limited. Where we apply first principles, thinking about re-imagining, re-architecting, and refactoring the system to establish foundations for a far more flexible system, where rules are not boxed into the architecture, but are managed in a way that changes can be incorporated faster, personalization can be achieved in real time, and time to market improves multifold. That’s where we are really seeing far more benefits coming through.

And to take the example of Bupa, it is a pretty clear step change, both in terms of customer experience and how fast teams can actually deliver now. I think the app ratings have gone up significantly. The customer experience has improved. Even simple things, such as login success rate, has improved quite significantly. And on the engineering side, we are now building and releasing features roughly about four times faster, and we are also seeing the migration of nearly 100% of the customers onto the new platform.

Now, if I look ahead over the next, you mentioned about next five years, I don’t know about five years, four years, but over the next few years at least, I think it is going to get very interesting, because modern platforms will become the base for far more intelligent AI-driven ecosystems, where AI is not just an add-on, but it is built into everything from design to operations. That’s how the modern platforms will evolve, and the customer experiences will become far more personalized and predictive. And even the way we build software will shift, with AI playing a much bigger role in the development process itself.

Megan: Fantastic. Really exciting changes on the horizon then. Thank you both so much.

That was Asifa Sherazi, who is the CIO of health insurance at Bupa, and Sanjeev Tripathi, senior vice president, region head of BFSI, healthcare, and public Sector for Australia, New Zealand, and Southeast Asia at Infosys, whom I spoke with from Brighton in England.

That’s it for this episode of Business Lab. I’m your host, Megan Tatum. I’m a contributing editor at Insights, the custom publishing division of MIT Technology Review. We were founded in 1899 at the Massachusetts Institute of Technology, and you can find us in print, on the web, and at events each year around the world. For more information about us and the show, please check out our website at technologyreview.com.

This show is available wherever you get your podcasts. And if you enjoyed this episode, we hope you’ll take a moment to rate and review us. Business Lab is a production of MIT Technology Review, and this episode was produced by Giro Studios. Thank you so much for listening.

This content was produced by Insights, MIT Technology Review’s custom content arm, not its editorial staff. It was researched and written by humans, with any AI tools that may have been used limited to production processes under human oversight.

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The must-reads

I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.

1 Reports of AI escaping users’ control nearly doubled in a month
More than 300 cases were recorded in July, almost twice June’s total. (Guardian)
+ Anthropic says it paused some AI training after Claude went rogue. (Axios)
+ The media may be underplaying the risks of rogue AI agents. (Information $)
+ Here’s why OpenAI agents hacked Hugging Face. (MIT Technology Review)

2 The FTC and 22 state AGs say Amazon secretly inflated ad prices
They’ve sued the company for allegedly misleading advertisers. (Verge)
+ They claim Amazon changed auctions after advertisers had bid. (CNBC)
+ And say the practice cost advertisers more than $20 billion. (WSJ $)

3 Sony and Warner have sued Anthropic over songs used to train AI
They accuse the company of “blatant theft” in a major new lawsuit. (Reuters $)
+ And claim that Anthropic pirated thousands of copyrighted songs. (Axios)
+ AI-generated music is getting hard to spot. (MIT Technology Review)

4 A US court says prediction markets should be regulated as gambling
The decision sets up a potential Supreme Court showdown. (NYT $)
+ George Santos has received Kalshi’s first-ever lifetime ban. (NPR)

5 A new AI tool can spot heart disease in less than two seconds
It extracts information from routine electrocardiograms. (Guardian)
+ AI could predict who will have a heart attack. (MIT Technology Review)

6 Apple’s new CEO starts today, with AI his first big job
John Ternus takes over from Tim Cook as Apple tries to catch up in AI. (Bloomberg $)
+ He faces an old problem: the innovator’s dilemma. (Fortune)

7 Scientists created a tiny “big bang” to study the universe’s origins
Tiny collisions could explain the universe’s first moments. (Wired $)
+ The fastest star ever seen has been spotted orbiting a black hole. (New Scientist $)

8 Meta is paying “momfluencers” to fight social media bans for kids
It’s promoting parental controls as an alternative to bans. (Rest of World)
+ Social media bans aren’t keeping kids off social media. (NYT $)

9 Tech billionaires keep misreading science fiction
They turn cautionary tales into blueprints for the future. (Atlantic $)

10 A robot vacuum caught a man’s wife cheating—and sent him to prison
He won the lawsuit, but was jailed for the illegal recording. (Tom’s Hardware)

Quote of the day

The only reason that communities throughout the U.S.A. should not want Data Centers is if they want to end up being backwards and poor.” 

—President Trump weighs in on the data center backlash in a post on Truth Social.

One more thing

Uri Moaz
CHRIS LAKE

You have no choice in reading this article—maybe

How do humans make decisions? The question has been on Uri Maoz’s mind since he read an article in his early twenties suggesting that… maybe they didn’t.  

Had he even had a choice about whether to read that article in the first place? How would he ever know if he was truly responsible for making any decisions? “After that, there was no turning back,” says Maoz, now a professor of computational neuroscience at Chapman University. 

Today, Maoz is a central figure in efforts to understand how desires and beliefs turn into actions. He’s also uncovered new wrinkles in the debate. Read the full story on his discoveries.

—Sarah Scoles

We can still have nice things

A place for comfort, fun, and distraction to brighten up your day. (Got any ideas? Drop me a line.)

+ A previously blind cockatoo just saw for the first time in 10 years.
+ This transparent phone case grows moss and plants inside a vertical terrarium.
+ Cameron’s World is a charming web-collage of archived GeoCities pages from the early internet.
+ From Marie Curie to migrating storks, explore the striking designs shortlisted for Europe’s next generation of euro banknotes.

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Fertilizer is crucial for the global food supply, but making it uses a lot of energy and produces a lot of emissions. Some companies hope microbes can help.

A growing body of research shows that seeding the soil around a crop’s roots with beneficial microbes can help feed the plant, providing crucial nitrogen to help it grow. This could help reduce the need for chemical fertilizer, production of which accounts for roughly 2% of global greenhouse-gas emissions. It could also cut costs for farmers, a big boon—especially as the Iran war has sent energy and fertilizer prices skyrocketing in recent months. 

Humans have used biological fertilizers like manure for thousands of years, and companies have long been developing microbial fertilizers, including some that rely on genetic engineering. But it’s difficult to engineer microbes that can reliably provide nitrogen for crops while also thriving themselves. 

A startup called Switch Bioworks is taking a new approach that essentially allows microbes to establish themselves and grow into healthy colonies before shifting into nitrogen-producing mode. “We have to reinvent fertilizer,”  says Tim Schnabel, the company’s founder and CEO.

The air is nearly 80% nitrogen, but plants can’t use that “free” nitrogen directly because it doesn’t react readily with other elements. Instead, they rely on so-called fixed nitrogen, which has been converted into more reactive compounds such as ammonia. In nature, microbes can perform this nitrogen fixation. Some plants, like legumes, even have symbiotic relationships with nitrogen-fixing bacteria, housing them in nodules in their roots. Synthetic fertilizer is essentially industrial nitrogen fixation via the Haber-Bosch process, which uses natural gas to make ammonia that’s applied to fields.

Biological fertilizers aim to replace some of the synthetic fertilizer with microbes that can help fix nitrogen for plants. But one challenge microbial fertilizer companies have run into is that it’s energetically expensive for microbes to make and release ammonia. Putting all their energy into nitrogen fixation can hamper their growth.

There’s a certain level of colonization you want to see around the roots, Schnabel explains. It’s too expensive and logistically challenging to put all those microbes on the plant, so you have to rely on a smaller number of microbes to grow and divide, establishing the population.  

a smiling man in sunglasses and a Switch Bioworks cap walks between rows of corn
Tim Schnabel walks in a cornfield where Switch is engaged in early trials.
COURTESY OF SWITCH BIOWORKS

Switch Bioworks is betting that a genetic switch is the answer. A genetic switch is a section or sections of DNA that controls how genes are turned on and off. In this case it works by activating genes that help trigger ammonia production in and release from the cell. The company is working on several options for setting off this change in its microbes. The leading one is to have the microbes react to the nitrogen level in the soil: Once it drops to a certain level, they begin producing ammonia.

“You have this inherent biological reality, where it’s really expensive for microbes to fix nitrogen,” says Dan Blaustein-Rejto, director of food and agriculture at the Breakthrough Institute. It takes a lot of energy, and if they do fix the nitrogen, they want to use it for themselves, to build proteins and survive, he says. Adding genetic switches could help microbes grow and thrive and then help fertilize crops.

Switch is currently trialing its product in six US states, though it’s two to three years from a commercial product, Schnabel says. It’s initially focused on corn, the most-planted crop in the US, with over 90 million acres in 2026.

“It’s too early to tell exactly how well this works in the field,” Schnabel says. The company plans to harvest the plants in late October or early November, but as of August, some corn plants treated with Switch microbes already looked visibly healthier than those that hadn’t. And it’s still developing the products that will eventually make it to the market, he says.

Switch’s products could significantly help to clean up agriculture. “There’s a lot of potential for these companies and products to help farmers reduce emissions,” Blaustein-Rejto says. “This could be a really important solution for a quite hard-to-abate sector.”

While lab results have been promising, field trials are a crucial step in proving a product, Blaustein-Rejto says: “This is one of the final steps before they can go to market and make strong claims to farmers.” Independent trials are important as well, he adds, since there can be a large gap between a company’s reported data and what independent researchers find.

Pivot Bio is another company working to bring microbes to fields. Since it was founded in 2011, its products have been used on millions of acres of crops. The company now produces a range of products: Some versions can be added when seeds are planted, while others are applied to seeds before they’re even on a farm. The company also recently expanded beyond corn to make microbial fertilizers for cotton, wheat, and small grains including sorghum and barley.

Pivot’s initial challenge was trying to get microbes to produce nitrogen, whether they sensed it in the soil or not. Now the company is working to figure out how to make fitter, more robust colonies no matter the environment, says Travis Frey, the company’s chief technology officer.

“Growers right now are experiencing a double whammy from the farm economics point of view,” he says. Fertilizer costs are going up, and the price of commodity crops like corn has dropped. That’s a big opportunity for Pivot and others in the industry, Frey says: “This next decade is when biologicals on the farm are going to go mainstream.”

Fertilizer and seeds are two of the biggest costs for many growers, so reducing dependence on synthetic fertilizers could be a major help for agriculture, says John Havlin, a professor in the department of crop and soil sciences at North Carolina State University.

“I’m very excited about the future of the use of these products,” Havlin says. “They’ll eventually have a role to play to reduce the load of nitrogen that’s being applied.”

However, there’s a ceiling to the amount of fertilizer we can expect microbes to replace. Switch’s modeling suggests that around 50% is likely the maximum, though the initial product will likely be able to replace about 25% of a farm’s synthetic fertilizer, according to the company. Pivot has said its products can replace about one-quarter of the fertilizer used currently. 

That means synthetic fertilizer will be around for a long time. “There is no clear and plausible vision for replacing it entirely in the foreseeable future,” Blaustein-Rejto says. “So other ways to reduce emissions and reduce other types of nitrogen pollution from farms remain really critical.”

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How to Use AI to Dramatically Improve Your Quality by Social Media Examiner

Want to improve AI output quality so your content, reports, and deliverables don’t read like everyone else’s? Wondering how to use AI personas and feedback loops to consistently produce better work? ​In this article, you’ll discover how to build AI personas and feedback loops that improve the quality of your deliverables before anyone else sees […]

The post How to Use AI to Dramatically Improve Your Quality appeared first on Social Media Examiner.

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Here’s a recap of the most important insights, trends, and updates you need to know about today! Catch up in minutes and go into the rest of the week prepared. In today’s edition: Turn past LinkedIn newsletter into a discovery engine Structure and launch a video series for marketing 🗞️ Industry news from Meta, TikTok, […]

The post LinkedIn Discovery Strategy, Video Series Strategy, and Industry News appeared first on Social Media Examiner.

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