
Robust onchain activity, a resilient futures market and improving investor optimism boost the chance for ETH to hit $5,000.


Robust onchain activity, a resilient futures market and improving investor optimism boost the chance for ETH to hit $5,000.

The judge suggested that a brief stay while awaiting a ruling in a similar case in the appellate court could “reduce the burden of litigation.”
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.
In a first, Google has released data on how much energy an AI prompt uses
Google has just released a report detailing how much energy its Gemini apps use for each query. In total, the median prompt—one that falls in the middle of the range of energy demand—consumes 0.24 watt-hours of electricity, the equivalent of running a standard microwave for about one second. The company also provided average estimates for the water consumption (five drops per query) and carbon emissions associated with a text prompt to Gemini.
It’s the most transparent estimate yet from a Big Tech company with a popular AI product, and the report includes detailed information about how the company calculated its final estimate.
Earlier this year, MIT Technology Review published a comprehensive series on AI and energy, at which time none of the major AI companies would reveal their per-prompt energy usage. Google’s new publication, at last, allows for a peek behind the curtain that researchers and analysts have long hoped for. Read the full story.
—Casey Crownhart
I gave the police access to my DNA—and maybe some of yours
Last year, I added my DNA profile to a private genealogical database, FamilyTreeDNA, and clicked “Yes” to allow the police to search my genes.
In 2018, police in California announced they’d caught the Golden State Killer, a man who had eluded capture for decades. Once the police had “matches” to a few relatives of the killer, they built a large family tree from which they plucked the likely suspect.
This process, called forensic investigative genetic genealogy, or FIGG, has since helped solve hundreds of murders and sexual assaults.
But I wasn’t really driven by some urge to capture distantly related serial killers. Rather, my spit had a less gallant and more quarrelsome motive: to troll privacy advocates whose fears around DNA I think are overblown and unhelpful. By giving up my saliva for inspection, I was going against the view that a person’s DNA is the individualized, sacred text that privacy advocates sometimes claim. Read the full story.
—Antonio Regalado
This article appeared in The Checkup, MIT Technology Review’s weekly biotech newsletter. To receive it in your inbox every Thursday, and read articles like this first, sign up here.
Meet the researcher hosting a scientific conference by and for AI
In October, a new academic conference will debut that’s unlike any other. All of the work shared at Agents4Science will have been researched, written, and reviewed primarily by AI, and will be presented using text-to-speech technology.
That idea is not without its detractors. Among other issues, many feel AI is not capable of the creative thought needed in research, makes too many mistakes and hallucinations, and may limit opportunities for young researchers.
Nevertheless, a number of scientists and policymakers are very keen on the promise of AI scientists—and some even think they could unlock scientific discoveries that humans could never find alone. Read the full story.
—Peter Hall
The must-reads
I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.
1 Elon Musk tried to persuade Mark Zuckerberg to buy OpenAI
But the bid was rejected earlier this year. (Insider $)
+ OpenAI is asking Meta for evidence of any coordinated plans. (TechCrunch)
+ I’m guessing the cage fight is still off then. (FT $)
2 AI giants are seeking real-world data that can’t be scraped from the internet
It’s a bid to make their models more accurate and to find new use cases. (Rest of World)
3 Russia’s state-backed messenger app will be preinstalled on all phones
Critics say the MAX app is essentially a government spy tool. (Reuters)
+ Around 18 million people have registered to use it so far. (CNN)
+ How Russia killed its tech industry. (MIT Technology Review)
4 The Trump administration is refusing to fully fund a major HIV program
It’s ignoring a directive from Congress to withhold around $3 billion. (NYT $)
+ HIV could infect 1,400 infants every day because of US aid disruptions. (MIT Technology Review)
5 How Trump decides which chip companies may have to give up equity
Increasing your investments in the US? You’re off the hook. (WSJ $)
+ America-first chipmaking remains a fantasy, though. (Economist $)
+ Experts think Trump’s unconventional Intel deal may backfire. (Wired $)
+ DeepSeek’s new AI model is compatible with Chinese-made chips. (FT $)
6 The EU is speeding up its plans for a digital euro 
It’s considering running it on a public blockchain, to experts’ concern. (FT $)
+ Is the digital dollar dead? (MIT Technology Review)
7 We don’t have to open new mines to obtain minerals for clean energy
Although we have to get better at using the material we do mine. (New Scientist $)
+ How one mine could unlock billions in EV subsidies. (MIT Technology Review)
8 This newly-discovered gene could usher in new chronic pain treatments
One day, cutting out certain foods could lessen discomfort. (Economist $)
+ The pain is real. The painkillers are virtual reality. (MIT Technology Review)
9 Why Africa is buying so many solar panels
It’s not just its more affluent nations snapping them up, either. (Wired $)
+ The race to get next-generation solar technology on the market. (MIT Technology Review)
10 How families are using AI to run their households
No more quibbling over meal planning. (WP $)
Quote of the day
“If AGI doesn’t come to pass sometime soon, I wouldn’t be surprised if this whole thing pops.”
—Bhavya Kashyap, an angel investor, tells Insider why investors are fuelling a risky bubble by rushing to buy stocks in the hottest AI companies.
One more thing

How AI is changing gymnastics judging
The 2023 World Championships last October marked the first time an AI judging system was used on every apparatus in a gymnastics competition. There are obvious upsides to using this kind of technology: AI could help take the guesswork out of the judging technicalities. It could even help to eliminate biases, making the sport both more fair and more transparent.
At the same time, others fear AI judging will take away something that makes gymnastics special. Gymnastics is a subjective sport, like diving or dressage, and technology could eliminate the judges’ role in crafting a narrative.
For better or worse, AI has officially infiltrated the world of gymnastics. The question now is whether it really makes it fairer. Read the full story.
—Jessica Taylor Price
We can still have nice things
A place for comfort, fun and distraction to brighten up your day. (Got any ideas? Drop me a line or skeet ’em at me.)
+ Finally, some good news—a sweet little Australian marsupial called an ampurta is no longer endangered (thanks Glen!)
+ What would a GTA set in London look like?
+ Why glass houses aren’t all they’re cracked up to be (geddit?)
+ Over in Denmark, there’s a national competition encouraging cities to get rid of their gray concrete tiles and replace them with peaceful green spaces (thanks Alice!)
In October, a new academic conference will debut that’s unlike any other. Agents4Science is a one-day online event that will encompass all areas of science, from physics to medicine. All of the work shared will have been researched, written, and reviewed primarily by AI, and will be presented using text-to-speech technology.
The conference is the brainchild of Stanford computer scientist James Zou, who studies how humans and AI can best work together. Artificial intelligence has already provided many useful tools for scientists, like DeepMind’s AlphaFold, which helps simulate proteins that are difficult to make physically. More recently, though, progress in large language models and reasoning-enabled AI has advanced the idea that AI can work more or less as autonomously as scientists themselves—proposing hypotheses, running simulations, and designing experiments on their own.

That idea is not without its detractors. Among other issues, many feel AI is not capable of the creative thought needed in research, makes too many mistakes and hallucinations, and may limit opportunities for young researchers.
Nevertheless, a number of scientists and policymakers are very keen on the promise of AI scientists. The US government’s AI Action Plan describes the need to “invest in automated cloud-enabled labs for a range of scientific fields.” Some researchers think AI scientists could unlock scientific discoveries that humans could never find alone. For Zou, the proposition is simple: “AI agents are not limited in time. They could actually meet with us and work with us 24/7.”
Last month, Zou published an article in Nature with results obtained from his own group of autonomous AI workers. Spurred on by his success, he now wants to see what other AI scientists (that is, scientists that are AI) can accomplish. He describes what a successful paper at Agents4Science will look like: “The AI should be the first author and do most of the work. Humans can be advisors.”
As a PhD student at Harvard in the early 2010s, Zou was so interested in AI’s potential for science that he took a year off from his computing research to work in a genomics lab, in a field that has greatly benefited from technology to map entire genomes. His time in so-called wet labs taught him how difficult it can be to work with experts in other fields. “They often have different languages,” he says.
Large language models, he believes, are better than people at deciphering and translating between subject-specific jargon. “They’ve read so broadly,” Zou says, that they can translate and generalize ideas across science very well. This idea inspired Zou to dream up what he calls the “Virtual Lab.”
At a high level, the Virtual Lab would be a team of AI agents designed to mimic an actual university lab group. These agents would have various fields of expertise and could interact with different programs, like AlphaFold. Researchers could give one or more of these agents an agenda to work on, then open up the model to play back how the agents communicated to each other and determine which experiments people should pursue in a real-world trial.
Zou needed a (human) collaborator to help put this idea into action and tackle an actual research problem. Last year, he met John E. Pak, a research scientist at the Chan Zuckerberg Biohub. Pak, who shares Zou’s interest in using AI for science, agreed to make the Virtual Lab with him.
Pak would help set the topic, but both he and Zou wanted to see what approaches the Virtual Lab could come up with on its own. As a first project, they decided to focus on designing therapies for new covid-19 strains. With this goal in mind, Zou set off training five AI scientists (including ones trained to act like an immunologist, a computational biologist, and a principal investigator) with different objectives and programs at their disposal.
Building these models took a few months, but Pak says they were very quick at designing candidates for therapies once the setup was complete: “I think it was a day or half a day, something like that.”
Zou says the agents decided to study anti-covid nanobodies, a cousin of antibodies that are much smaller in size and less common in the wild. Zou was shocked, though, at the reason. He claims the models landed on nanobodies after making the connection that these smaller molecules would be well-suited to the limited computational resources the models were given. “It actually turned out to be a good decision, because the agents were able to design these nanobodies efficiently,” he says.
The nanobodies the models designed were genuinely new advances in science, and most were able to bind to the original covid-19 variant, according to the study. But Pak and Zou both admit that the main contribution of their article is really the Virtual Lab as a tool. Yi Shi, a pharmacologist at the University of Pennsylvania who was not involved in the work but made some of the underlying nanobodies the Virtual Lab modified, agrees. He says he loves the Virtual Lab demonstration and that “the major novelty is the automation.”
Nature accepted the article and fast-tracked it for publication preview—Zou knew leveraging AI agents for science was a hot area, and he wanted to be one of the first to test it.
When he was submitting his paper, Zou was dismayed to see that he couldn’t properly credit AI for its role in the research. Most conferences and journals don’t allow AI to be listed as coauthors on papers, and many explicitly prohibit researchers from using AI to write papers or reviews. Nature, for instance, cites uncertainties over accountability, copyright, and inaccuracies among its reasons for banning the practice. “I think that’s limiting,” says Zou. “These kinds of policies are essentially incentivizing researchers to either hide or minimize their usage of AI.”
Zou wanted to flip the script by creating the Agents4Science conference, which requires the primary author on all submissions to be an AI. Other bots then will attempt to evaluate the work and determine its scientific merits. But people won’t be left out of the loop entirely: A team of human experts, including a Nobel laureate in economics, will review the top papers.
Zou isn’t sure what will come of the conference, but he hopes there will be some gems among the hundreds of submissions he expects to receive across all domains. “There could be AI submissions that make interesting discoveries,” he says. “There could also be AI submissions that have a lot of interesting mistakes.”
While Zou says the response to the conference has been positive, some scientists are less than impressed.
“How do you get leaps of insight?”
Lisa Messeri
Lisa Messeri, an anthropologist of science at Yale University, has loads of questions about AI’s ability to review science: “How do you get leaps of insight? And what happens if a leap of insight comes onto the reviewer’s desk?” She doubts the conference will be able to give satisfying answers.
Last year, Messeri and her collaborator Molly Crockett investigated obstacles to using AI for science in another Nature article. They remain unconvinced of its ability to produce novel results, including those shared in Zou’s nanobodies paper.
“I’m the kind of scientist who is the target audience for these kinds of tools because I’m not a computer scientist … but I am doing computationally oriented work,” says Crockett, a cognitive scientist at Princeton University. “But I am at the same time very skeptical of the broader claims, especially with regard to how [AI scientists] might be able to simulate certain aspects of human thinking.”
And they’re both skeptical of the value of using AI to do science if automation prevents human scientists from building up the expertise they need to oversee the bots. Instead, they advocate for involving experts from a wider range of disciplines to design more thoughtful experiments before trusting AI to perform and review science.
“We need to be talking to epistemologists, philosophers of science, anthropologists of science, scholars who are thinking really hard about what knowledge is,” says Crockett.
But Zou sees his conference as exactly the kind of experiment that could help push the field forward. When it comes to AI-generated science, he says, “there’s a lot of hype and a lot of anecdotes, but there’s really no systematic data.” Whether Agents4Science can provide that kind of data is an open question, but in October, the bots will at least try to show the world what they’ve got.
Elon Musk and Jeff Bezos are bitter rivals in the commercial space race, but they agree on one thing: Settling space is an existential imperative. Space is the place. The final frontier. It is our human destiny to transcend our home world and expand our civilization to extraterrestrial vistas.
This belief has been mainstream for decades, but its rise has been positively meteoric in this new gilded age of astropreneurs. Expanding humanity beyond Earth is both our birthright and our duty to the future, they insist. Failing to do so would consign our species to certain extinction—either by our own hand, perhaps through nuclear war or climate change, or in some cosmic disaster, like a massive asteroid impact.
But as visions of giant orbital stations and Martian cities dance in our heads, a case against human space colonization has found its footing in a number of recent books. The argument grows from many grounds: Doubts about the practical feasibility of off-Earth communities. Concerns about the exorbitant costs, including who would bear them and who would profit. Realism about the harsh environment of space and the enormous tax it would exact on the human body. Suspicion of the underlying ideologies and mythologies that animate the race to settle space.
And, more bluntly, a recognition that “space sucks” and a lot of people have “underestimated the scale of suckitude,” as Kelly and Zach Weinersmith put it in their book A City on Mars: Can We Settle Space, Should We Settle Space, and Have We Really Thought This Through?, which was released in paperback earlier this year.

The Weinersmiths, a husband-wife team, spent years thinking it through—in delightfully pragmatic detail. A City on Mars provides ground truth for our lofty celestial dreams by gaming out the medical, technical, legal, ethical, and existential consequences of space settlements.
Much to the authors’ own dismay, the result is a grotesquery of possible outcomes including (but not limited to) Martian eugenics, interplanetary war, and—memorably—“space cannibalism.”
The Weinersmiths puncture the gauzy fantasy of space cities by asking pretty basic questions, like how to populate them. Astronauts experience all kinds of medical challenges in space, such as radiation exposure and bone loss, which would increase risks to both parents and babies. Nobody wants their pregnant “glow” to be a by-product of cosmic radiation.
Trying to bring forth babies in space “is going to be tricky business, not just in terms of science, but from the perspective of scientific ethics,” they write. “Adults can consent to being in experiments. Babies can’t.”
You don’t even have to contemplate going to Mars to make some version of this case. In Ground Control: An Argument for the End of Human Space Exploration, Savannah Mandel chronicles how past and present generations have regarded human spaceflight as an affront to vulnerable children right here on Earth.

“Hungry Kids Can’t Eat Moon Rocks,” read signs at a protest outside Kennedy Space Center on the eve of the Apollo 11 launch in July 1969. Gil Scott-Heron’s 1970 poem “Whitey on the Moon” rose to become the de facto anthem of this movement, which insists, to this day, that until humans get our earthly house in order, we have no business building new ones in outer space.
Ground Control, part memoir and part manifesto, channels this lament: How can we justify the enormous cost of sending people beyond our planet when there is so much suffering here at home?
Advocates for human space exploration reject the zero-sum framing and point to the many downstream benefits of human spaceflight. Space exploration has catalyzed inventions from the CAT scan to baby formula. There is also inherent value in our shared adventure of learning about the vast cosmos.
Those upsides are real, but they are not remotely well distributed. Mandel predicts that the commercial space sector in its current form will only exacerbate inequalities on Earth, as profits from space ventures flow into the coffers of the already obscenely rich.
In her book, Mandel, a space anthropologist and scholar at Virginia Tech, describes a personal transformation from spacey dreamer to grounded critic. It began during fieldwork at Spaceport America, a commercial launch facility in New Mexico, where she began to see cracks in the dazzling future imagined by space billionaires. As her career took her from street protests in London to extravagant space industry banquets in Washington, DC, she writes, “crystal clear glasses” replaced “the rose-colored ones.”
Mandel remains enchanted by space but is skeptical that humans are the optimal trailblazers. Robots, rovers, probes, and other artificial space ambassadors could do the job for a fraction of the price and without risk to life, limb, and other corporeal vulnerabilities.
“A decentralization of self needs to occur,” she writes. “A dissolution of anthropocentrism, so to speak. And a recognition that future space explorers may not be man, even if man moves through them.”
In other words, giant leaps for mankind no longer necessitate a man’s small steps; the wheels of a rover or the rotors of a copter offer a much better bang for our buck than boots on the ground.
In contrast to the Weinersmiths, Mandel devotes little attention to the physical dangers and limitations that space imposes on humans. She is more interested in a kind of psychic sickness that drives the impulse to abandon our planet and rush into new territories.
Mary-Jane Rubenstein, a scholar of religion at Wesleyan University, presents a thorough diagnosis of this exact pathology in her 2022 book Astrotopia: The Dangerous Religion of the Corporate Space Race, which came out in paperback last year. It all begins, appropriately enough, with the book of Genesis, where God creates Earth for the dominion of man. Over the years, this biblical brain worm has offered divine justification for the brutal colonization and environmental exploitation of our planet. Now it serves as the religious rocket fuel propelling humans into the next frontier, Rubenstein argues.

“The intensifying ‘NewSpace race’ is as much a mythological project as it is a political, economic, or scientific one,” she writes. “It’s a mythology, in fact, that holds all these other efforts together, giving them an aura of duty, grandeur, and benevolence.”
Rubenstein makes a forceful case that malignant outgrowths of Christian ideas scaffold the dreams of space settlements championed by Musk, Bezos, and like-minded enthusiasts—even if these same people might never describe themselves as religious. If Earth is man’s dominion, space is the next logical step. Earth is just a temporary staging ground for a greater destiny; we will find our deliverance in the heavens.
“Fuck Earth,” Elon Musk said in 2014. “Who cares about Earth? If we can establish a Mars colony, we can almost certainly colonize the whole solar system.”
Jeff Bezos, for one, claims to care about Earth; that’s among his best arguments for why humans should move beyond it. If heavy industries and large civilian populations cast off into the orbital expanse, our home world can be, in his words, “zoned residential and light industry,” allowing it to recover from anthropogenic pressures.
Bezos also believes that space settlements are essential for the betterment of humanity, in part on the grounds that they will uncork our population growth. He envisions an orbital archipelago of stations, sprawled across the solar system, that could support a collective population of a trillion people. “That’s a thousand Mozarts. A thousand Einsteins,” Bezos has mused. “What a cool civilization that would be.”
It does sound cool. But it’s an easy layup for Rubenstein: This “numbers game” approach would also produce a thousand Hitlers and Stalins, she writes.
And that is the real crux of the argument against pushing hard torapidly expand human civilization into space: We will still be humans when we get there. We won’t escape our vices and frailties by leaving Earth—in fact, we may exacerbate them.
While all three books push back on the existential argument for space settlements, the Weinersmiths take the rebuttal one step further by proposing that space colonization might actually increase the risk of self-annihilation rather than neutralizing it.
“Going to space will not end war because war isn’t caused by anything that space travel is apt to change, even in the most optimistic scenarios,” they write. “Humanity going to space en masse probably won’t reduce the likelihood of war, but we should consider that it might increase the chance of war being horrific.”
The pair imagine rival space nations exchanging asteroid fire or poisoning whole biospheres. Proponents of space settlements often point to the fate of the dinosaurs as motivational grist, but what if a doomsday asteroid were deliberately flung between human cultures as a weapon? It may sound outlandish, but it’s no more speculative than a floating civilization with a thousand Mozarts. It follows the same logic of extrapolating our human future in space from our behavior on Earth in the past.
So should we just sit around and wait for our inevitable extinction? The three books have more or less the same response: What’s the rush? It is far more likely that humanity will be wiped out by our own activity in the near term than by any kind of cosmic threat. Worrying about the expansion of the sun in billions of years, as Musk has openly done, is frankly hysterical.
In the meantime, we have some growing up to do. Mandel and Rubenstein both argue that any worthy human future in space must adopt a decolonizing approach that emphasizes caretaking and stewardship of this planet and its inhabitants before we set off for others. They draw inspiration from science fiction, popular culture, and Indigenous knowledge, among other sources, to sketch out these alternative visions of an off-Earth future.
Mandel sees hope for this future in post-scarcity political theories. She cites various attempts to anticipate the needs of future generations—ideas found in the work of the social theorist Aaron Benanav, or in the values expressed by the Green New Deal, or in the fictional Ministry for the Future imagined by Kim Stanley Robinson in his 2020 novel of the same name. Whatever you think of the controversial 2025 book Abundance, by Ezra Klein and Derek Thompson, it is also appealing to the same demand for a post-scarcity road map.
To that end, Mandel envisions “the creation of a governing body that would require that techno-scientific plans, especially those with a global reach, take into consideration multigenerational impacts and multigenerational voices.”
For Rubenstein, religion is the poison, but it may also offer the cure. She sees potential in a revival of pantheism, which is the belief that all the contents of the universe—from rocks to humans to galaxies—are divine and perhaps alive on some level. She hasn’t fully converted herself to this movement, let alone become an evangelist, but she says it’s a spiritual direction that could be an effective counterweight to dominionist views of the universe.
“It doesn’t matter whether … any sort of pantheism is ‘true,’” she writes. “What matters is the way any given mythology prompts us to interact with the world we’re a part of—the world each of our actions helps to make and unmake. And frankly, some mythologies prompt us to act better than others.”
All these authors ultimately conclude that it would be great if humans lived in space—someday, if and when we’ve matured. But the three books all express concerns about efforts by commercial space companies, with the help of the US government, to bypass established space laws and norms—concerns that have been thoroughly validated in 2025.
The combustible relationship between Elon Musk and Donald Trump has raised eyebrows about cronyism—and retribution—between governments and space companies. Space is rapidly becoming weaponized. And recent events have reminded us of the immense challenges of human spaceflight. SpaceX’s next-generation Starship vehicle has suffered catastrophic failures in several test flights, while Boeing’s Starliner capsule experienced malfunctions that kept two astronauts on the International Space Station for months longer than expected. Even space tourism is developing a bad rap: In April, a star-studded all-woman crew on a Blue Origin suborbital flight was met with widespread backlash as a symbol of out-of-touch wealth and privilege.
It is at this point that we must loop back to the issue of “suckitude,” which Mandel also channels in her book through the killer opening of M.T. Anderson’s novel Feed: “We went to the moon to have fun, but the moon turned out to completely suck.”
The dreams of space settlements put forward by Musk and Bezos are insanely fun. The reality may well suck. But it’s doubtful that any degree of suckitude will slow down the commercial space race, and the authors do at times seem to be yelling into the cosmic void.
Still, the books challenge space enthusiasts of all stripes to imagine new ways of relating to space that aren’t so tactile and exploitative. Along those lines, Rubenstein shares a compelling anecdote in Astrotopia about an anthropologist who lived with an Inuit community in the early 1970s. When she told them about the Apollo moon landings, her hosts burst out in laughter.
“We didn’t know this was the first time you white people had been to the moon,” they said. “Our shamans go all the time … The issue is not whether we go to visit our relatives, but how we treat them and their homeland when we go.”
Becky Ferreira is a science reporter based in upstate New York, and author of First Contact, a book about the search for alien life, which will be published in September.