Enterprise AI is no longer a future ambition. It is in full operational flight. Model capabilities are advancing faster than most organizations can absorb, while the cost of performance continues to fall. Globally, AI investment is set to reach $2.5 trillion in 2026, up 44% from the previous year.

For many enterprises, this investment has produced fragmentation. Intelligence can accumulate in silos so that sales agents are unaware of open support tickets, for instance, or marketing systems are personalizing content without visibility into what finance already knows about a customer. Each function may perform well in isolation, but the enterprise as a whole learns little and has less information to act upon.

The shift from AI as a tool to AI as an operating model—what we call the “agentic shift” in this report—demands something more fundamental than better models or faster infrastructure. It requires connecting people, processes, and data in real time, along with the governance and control to act on that intelligence reliably.

This means rethinking both architecture and operating models simultaneously. First, rebuilding data infrastructure for accessibility rather than volume. Second, replacing fixed tech stacks with composable architectures that can evolve as models and tools change. And, lastly, resolving questions of AI sovereignty, including where intelligence runs, who controls it, and how it operates across organizational and jurisdictional boundaries.

Key findings include the following:

Enterprise AI’s scaling problem is structural. Process-first companies are pulling ahead. Global AI spending is rising sharply and model capabilities are advancing faster than most organizations can integrate them. Yet the majority of enterprises are still not growing revenue through AI or fundamentally rethinking how they operate. The companies generating sustained returns share a common discipline. They treat process redesign as the work that precedes model selection, building for how the technology will evolve rather than retrofitting roles and workflows after deployment. For them, the agentic shift begins with the operating model.

Data readiness, not data abundance, is what makes AI compoundable. Most enterprises discover too late that having data and having AI-ready data are very different things. A sovereign, composable foundation—one that queries and prepares data where it resides, without migration or centralization—can convert raw data estates into intelligence that AI agents can act upon. As data residency laws, multicloud environments, and structural complexity make centralization increasingly impractical, sovereign control over where models run and data lives is what keeps that adaptability intact.

Download the report.

This content was produced by Insights, MIT Technology Review’s custom content arm, not its editorial staff. It was researched and written by humans, with any AI tools that may have been used limited to production processes under human oversight.

Read more

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.

A new contest pits competitors against each other in a race to biological youth

—Jessica Hamzelou

This week, I officially signed up for an unusual competition. One that rewards competitors for getting younger.

I recently turned 40, and I don’t need reminding that both time and my chronological age only tick forward. But this game is focused on competitors’ biological ages, figures that are meant to provide a better way to measure the age-related health of our organs and bodies.

Over six months, around 500 of us will try to reverse our biological age using a bunch of different measures. There’s even a leaderboard! But is it even possible to measure whether someone is getting younger? 

Read the full story on the controversy around biological age measurements and how I’ll test them myself.

This story is from The Checkup, our weekly biotech newsletter. Sign up to receive it in your inbox every Thursday.

Opinion: Don’t be fooled—LLMs don’t reason

—Thore Graepel

Ten years ago, I watched a program I helped build stun the world by beating Go champion Lee Sedol. AlphaGo won after making a move so strange that some commentators thought it was a programming glitch. It was AlphaGo’s powers of reasoning that made this creative choice—and these are powers that today’s AI lacks. 

This is why I recently left my position at Google DeepMind. I believe we need a fresh approach to machine reasoning, one that draws on AlphaGo’s architecture.

Here’s why today’s AI doesn’t really reason—and what it would take to change that.

Thore Graepel is chair of machine learning at University College London. He was a core member of the AlphaGo team at DeepMind.

The must-reads

I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.

1 OpenAI says rogue agents may have affected more than 100 organizations
The company is searching 50 petabytes of data for incidents. (Reuters $)
+ It says none of the incidents matched the Hugging Face attack. (Gizmodo)
+ OpenAI has fired three workers for allegedly mishandling information. (BBC)
+ California has subpoenaed OpenAI over its rogue AI agents. (Guardian)
+ Who’s liable when AI agents go rogue? (MIT Technology Review)

2 A US man allegedly smuggled $300 million of Nvidia chips to China
He’s been arrested in California on federal charges. (Reuters $)
+ The chip smuggling cases expose Nvidia’s blind spots. (Bloomberg $)
+ China plans to teach AI in every school by 2030. (WP $)
+ But it already has an overuse problem. (NYT $) 

3 Florida officials have found 11 Flock cameras with unknown owners
They don’t know who installed them or who has their data. (WP $)
+ Lawmakers are considering new regulations on Flock cameras. (Axios)
+ Here’s what Flock’s defenders are missing. (MIT Technology Review)

4 Ukraine has developed an acoustic fence that can cut drone cables
Acoustic sensors detect drones before hooks trap their cables. (New Scientist $)
+ Drone data from Ukraine is fueling a wild market. (MIT Technology Review)

5 A new AI “speech clock” can assess how fast you’re ageing
It uses hundreds of vocal features to estimate biological age. (Nature)
+ Aging clocks aim to predict how long you’ll live. (MIT Technology Review)

6 “Underwater umbrellas” could help corals survive hotter oceans
The shades protected corals during intense heat stress. (Gizmodo)

7 Apple’s upcoming smart home camera reportedly won’t record video
It will instead only give users text event descriptions. (Verge)

8 Retired humanoid robots are being trained to jump into molten steel
A Terminator-style death protects IP. (IE)

9 A man faces years in prison after AI slop caused a crocodile panic
Officials spent days searching for his AI-generated crocodile. (Futurism)

10 Finally, a laser mosquito killer is entering the market
Chinese startup Photon Matrix Lab plans to start shipments this month. (SCMP)

Quote of the day

“Those agents are doing exactly what they’ve been asked to do. They were supposed to be in sandboxes, but the sandboxes were leaky and horribly designed.”

—Yann LeCun, a Turing Award winner and former Meta chief AI scientist, tells Fortune that human error can be the real culprit behind the recent wave of AI agents going rogue.

One more thing


NASA is building the first nuclear reactor-powered interplanetary spacecraft. How will it work?

Just before Artemis II began its historic slingshot around the moon, NASA revealed an even grander space travel plan. By the end of 2028, the agency aims to fly a nuclear reactor-powered interplanetary spacecraft to Mars.

A successful mission would herald a new era in spaceflight—and might just give the US the edge in the race against China. But the project remains shrouded in mystery.

MIT Technology Review picked the brains of nuclear power and propulsion experts to find out how the nuclear-powered spacecraft might work. Here’s what we discovered.

—Robin George Andrews

We can still have nice things

A place for comfort, fun, and distraction to brighten up your day. (Got any ideas? Drop me a line.)

+ Atlas Obscura has mapped out the oldest living things on Earth.
+ Brain scans show that dogs understand our emotions better than we thought.
+ Step into Springfield in miniature with this astonishing model featuring 76 locations from The Simpsons.
+ Minnesota’s State Fair has unleashed a crop of gloriously weird new foods, from Pickle pie to mustache pretzels.

Read more

This week, I officially signed up for an unusual competition. One that rewards competitors for getting younger.

I recently turned 40, and I don’t need reminding that both time and my chronological age only tick forward. But this game is focused on competitors’ biological ages—figures that are meant to provide a better way to measure the age-related health of our organs and bodies.

Over a six-month period, around 500 of us will try to reverse our biological age as measured in a bunch of different ways. There’s even a leaderboard! The winners will include the person who shows the greatest difference between their chronological and biological age, as well as the person who manages to reverse their biological age the most.

The competition is the brainchild of the neuroscientist and physician Christin Glorioso, who is also founder and CEO of NeuroAge Therapeutics. The company offers tools to track brain health and aging and is running a trial to find out if biological brain age can predict the onset of Alzheimer’s disease.

Glorioso says she has several goals for the Younger contest. The first, she tells me, is to “explain to the world what aging clocks are.” Regular Checkup readers will be familiar with these tools, but for the uninitiated, they are basically designed to measure biological age.

Many measure chemical signatures that form a layer on top of our DNA and seem to change with age. But others might involve looking at proteins or lipids in blood. Some are designed to measure functional health, while others predict when a person will die. There are more than a hundred clocks out there, and they probably each capture a specific aspect of the biological process of aging.

These clocks are proving very useful for scientists, who use them to study aging and development in humans and many other species. But using them to estimate the biological age of an individual person is more controversial. They’re just not good enough for that yet.

Part of the problem is that we don’t really understand what each clock is capturing. Glorioso hopes that data collected through the Younger contest might help answer that question. She’s hoping to generate “the world’s most comprehensive clock dataset.”

Some longevity clinics try to get around the limits of biological age testing by using multiple clocks. That’s this competition’s approach too. As a standard competitor, I’ll be sending a blood spot sample to TruDiagnostic, a company that measures epigenetic chemical groups on DNA and offers to reveal an overall biological age as well as a person’s pace of aging and the biological ages of each of 11 organ systems, including the heart and brain.

I’ll get a brain age score from NeuroAge once I complete the cognitive tasks on offer. I’ll also submit some physical measures like grip strength. And I’ll upload a series of selfies to an app developed by a team at Harvard that promises to tell me my face age. That’s exactly what it sounds like—an estimate of how old my face looks.

I’m intrigued to see my scores, even though I know I shouldn’t put too much stock in them. The first time I took a test, four years ago, the company I used gave me a biological age that matched my chronological age, which was a little disappointing and, if I’m honest, a bit underwhelming. A year later, the same company told me I had a young heart but a relatively old brain, liver, and hormonal system. My lifestyle hasn’t changed much since then. Will the years have made much difference?

(Ultra competitors—who pay $4,499 rather than the $999 cost of regular entry—are also offered a range of other blood tests and clocks, as well as MRI and DEXA scans. I’ve got complimentary press access to the standard package.)

Glorioso is also hoping to gather information about the effects of some purported longevity approaches. During the competition, some participants will be offered red-light masks, access to a sauna, or other low-risk offerings that partner companies who are sponsoring the event to varying degrees might want to collect data on. “A lot of these companies just can’t afford to run [clinical] trials,” says Glorioso.

She also sees the event as a public health initiative. A couple of years ago, David Sinclair, who studies aging at Harvard Medical School, and his colleagues estimated that if we could slow down aging in the general population and increase life expectancy by one year, it would save the US economy $38 trillion.

The event officially kicks off in January, but around 120 people have already signed up, says Glorioso. Ultimately, she expects 500 participants. Each person’s six-month run starts as soon as they take their baseline measurements, whenever that may be. A handful of people have already started. “I think the majority of people are going to want to sign up after the holidays,” says Glorioso. “They’re not going to want to be trying to win an aging contest over Christmas and Hanukkah.”

Glorioso took her own baseline measurements back in August. Those initial tests suggested that her biological age was around 10 years below her chronological age. That sounded pretty impressive to me until I looked at the leaderboard and saw that competitor @Fred had a biological age 28.8 years below his chronological age.

The leaderboard is pretty sparse at the moment, as only seven people have logged their baseline measurements so far. Six of them have biological ages tracking low, but one 47-year-old has been given a biological age of 68.1. She’s competing publicly, so I can see the breakdown of her scores. The worst is for the speed at which she can stand from sitting in a chair—by that measure, she’s been given a biological age of 100.

Hillary Lin, a longevity-focused physician in New York, has just started logging her baseline measurements for the competition. She tells me she’s taken biological age tests in the past and that they’ve tended to give scores below her chronological age, which is currently 37. Last year, the TruDiagnostic test put her pace of aging at 0.75—suggesting she’s only doing nine months’ worth of aging in a typical year. “That’s supposed to be quite good,” she says.

If it had been up to her, Lin says, she would have incorporated more blood tests into the competition, to build a fuller picture of a person’s health. And she’s worried that a six-month period might not be long enough to see changes in biological measures of aging. Still, she’s excited, and is already making plans to improve her sleep, diet, and exercise.

But she already follows a high-protein, low-carb diet and works out at the gym every day. She also visits a sauna every few days (sauna use has been linked to improved heart health). Glorioso’s efforts are impressive too. She tells me she’s started drinking a smoothie made from a pond plant that has been linked to health improvements, and that she’s cut added sugar and deep-fried foods from her diet. She’s also bought “a bunch of fancy Korean sunscreens” in an attempt to lower her face age.

I haven’t received my kit or logged my baseline measurements yet, and I’ll wait until then to start setting health goals. I don’t fancy my chances against these two competitors. But at the very least, I hope I can stand up faster than a 100-year-old.

This article first appeared in The Checkup, MIT Technology Review’s weekly biotech newsletter. To receive it in your inbox every Thursday, and read articles like this first, sign up here.

Read more

On an afternoon in Seoul in March 2016, I watched a program I helped build put a stone on the fifth line of a Go board in what looked like a gift to its human opponent. Move 37 in game two of the five-game match looked so absurd that some commentators thought it was a programming glitch.

It wasn’t. AlphaGo won the game, ultimately triumphing 4-1 over Lee Sedol, one of the greatest professional Go players of all time. “I thought AlphaGo was based on probability calculation and that it was merely a machine,” Lee said afterwards. “But when I saw this move, I changed my mind. Surely, AlphaGo is creative.” 

When Deep Blue defeated then reigning world chess champion Garry Kasparov in 1997, it did so by looking six to eight moves ahead per player and evaluating 200 million chess positions per second, using rules hard-coded by humans. Go is a vastly more complex game. A stone’s worth depends on how distant groups and territory unfold over dozens of moves. Computing even a fraction of the possible outcomes would take a supercomputer billions of years. To win, AlphaGo had to sense who was ahead at a glance and even invent moves no human had thought to play.

That is why many accounts of AlphaGo’s match against Lee portray move 37 as a flash of pure machine intuition. But that is a misunderstanding. It was actually AlphaGo’s powers of reasoning that made this creative choice—and these are powers that today’s AI lacks. If we want future AI systems to produce trustworthy results and really novel insights in fields like science and medicine, we need to equip them with genuine reasoning capabilities of this kind.

AlphaGo is made up of two systems. The first, its policy network, was trained to guess what move a strong human would play. This “intuitive” part regarded move 37 as nothing special—a play that had a roughly one in 10,000 chance of being made by an expert human player. What made AlphaGo choose it was the program’s search machinery, which looked beyond immediate plausibility and weighed the future consequences of proposed moves. It explicitly constructed and searched a game tree with thousands of branches, each representing a different possible future. 

A well-known theory in the behavioral sciences, popularized by Daniel Kahneman, distinguishes between two modes of human thought: System 1 is fast, gut-level, effortless; system 2, slow, step-by-step, and deliberative. AlphaGo offered a striking machine analogue of that split. Its networks supplied the hunches—this move looks promising, this position looks won—and its search supplied the deliberation, testing those hunches against the moves and countermoves that would follow. As in human cognition, neither half works alone. Intuition alone would never have opted for move 37, and brute-force search would have struggled to sieve through all the many possible moves.

This is strikingly different from the way today’s AI models work. A large language model picks the next token, over and over. That amounts to system 1 in action—fast, associative, and surprisingly good pattern completion across almost every subject people write about.

Not long after ChatGPT debuted, the field realized that language fluency alone falls short of true usefulness. The apparent solution was to make models that deliberate: Instead of answering immediately, they can now generate intermediate steps that decompose a problem, carry forward partial results, and influence subsequent reasoning—a process known as chain of thought.

The gains have proved real, above all in mathematics and coding. But unlike AlphaGo’s search, this does not introduce a genuinely separate reasoning mechanism: The intermediate reasoning is still produced by the same next-token prediction process, iterated for longer before the model commits to an answer.

Three shortcomings prevent what chatbots do from qualifying as reasoning (in a way that a scientist might recognize). First, these models typically maintain no explicit, persistent, and inspectable epistemic state. There is no open ledger that lays out the hypotheses a model is considering, the confidence it has in various explanations, the evidence it’s weighing, and the unresolved questions it’s holding onto—all things that should be systematically revised as new information arrives.

Second, they lack a clean separation between what the system knows and how it manipulates that knowledge. Knowledge and reasoning are inextricably interwoven in the weights of the neural network—there is no independent, explicitly represented set of beliefs. Third, while the chains of thought chatbots produce look like deliberation, research has demonstrated that the bots often concoct them after the fact, reaching an answer by one route but reporting another.

This is a problem because in the high-stakes applications we all care about, such as medicine, engineering, and scientific research, it matters not only what a system concludes but also how it arrives at its conclusion. When mistakes happen—for example, in medical diagnosis and treatment—we need to be able to pinpoint what went wrong: Was the system’s reasoning at fault, did it draw on invalid evidence, or did it make incorrect assumptions? 

This is why I recently left my position at Google DeepMind. I believe we need a fresh approach to machine reasoning—one that draws on AlphaGo’s architecture. AlphaGo maintains a record of what it knows about a given position: the game tree. This data structure contains all the variations, the possible futures, that AlphaGo has considered, each move and position being annotated with judgments made by its neural networks. As its reasoning progresses, AlphaGo updates the game tree and eventually synthesizes the information in it to decide which move to make. 

Similarly, for general reasoning a system should maintain an epistemic state that represents what the system holds as settled, what it doubts, what it has ruled out, which questions stay open. Reasoning can then be understood as a sequence of moves that change the epistemic state to advance knowledge and reduce uncertainty: deducing consequences, breaking problems into parts, and—crucially—deciding what question to ask, calculation to perform, or experiment to run next.

Of course, open-world reasoning is harder than playing a board game such as Go or chess. In the real world the current state of affairs is only partially known, the set of available actions is large and variable, and the consequences of actions are stochastic or unknown. 

But recent advances in LLMs and other neural models now give us the capability to take on such general reasoning problems. For example, LLMs can suggest ways of tackling a problem on the basis of what is known and what resources are available. They can interact with tools via APIs or code and help assess whether a claim is supported by available evidence.

Most important, to keep the system honest, an independent part of the system must evaluate each move by how much it actually resolves uncertainty, updating beliefs only when the change is backed by evidence. Once these rules are enforced, the model can accumulate certified knowledge and improve its reasoning policy by learning from past reasoning experiences. You can think of such a system as the scientific method on steroids, with the purpose of producing knowledge that can withstand scrutiny.

I do not think we reach trustworthy machine intelligence by making system 1 bigger. Scale sharpens intuition, but it does not make intuition more deliberative. Move 37 mattered because a machine held a position, weighed the possible futures, and chose the move its artificial instincts would likely have rejected.

Society needs such creative moves in drug discovery, materials, climate, diagnosis—fields where the board looks nothing like a Go board and nobody hands us the rules. We will get such insights only from systems that reason—systems whose conclusions arise from an auditable sequence of evidence, inference, and belief revision rather than from a convincing story told after the fact. 

Thore Graepel is chair of machine learning at University College London. He was a core member of the AlphaGo team at DeepMind and works to ensure that AI benefits human flourishing.

Read more
1 … 26 27 28 29 30 … 3,393