For decades, manufacturers have pursued automation to drive efficiency, reduce costs, and stabilize operations. That approach delivered meaningful gains, but it is no longer enough.

Today’s manufacturing leaders face a different challenge: how to grow amid labor constraints, rising complexity, and increasing pressure to innovate faster without sacrificing safety, quality, or trust. The next phase of transformation will not be defined by isolated AI tools or individual robots, but by intelligence that can operate reliably in the physical world.

This is where physical AI—intelligence that can sense, reason, and act in the real world—marks a decisive shift. And it is why Microsoft and NVIDIA are working together to help manufacturers move from experimentation to production at industrial scale.

The industrial frontier: Intelligence and trust, not just automation

Most early AI adoption focused on narrow optimization: automating tasks, improving utilization, and cutting costs. While valuable, that phase often created new friction, including skills gaps, governance concerns, and uncertainty about long‑term impact. Furthermore, the use cases were plentiful but not as strategic.

The industrial frontier represents a different approach. Rather than asking how much work machines can replace, frontier manufacturers ask how AI can expand human capability, accelerate innovation, and unlock new forms of value while remaining trustworthy and controllable.

Across industries, companies that successfully move into this frontier phase share two non‑negotiables:

  • Intelligence: AI systems must understand how the business actually handles its data, workflows, and institutional knowledge.
  • Trust: As AI begins to act in high‑stakes environments, organizations must retain security, governance, and observability at every layer.

Without intelligence, AI becomes generic. Without trust, adoption stalls.

Why manufacturing is the proving ground for physical AI

Manufacturing is uniquely positioned at the center of this shift.

AI is no longer confined to planning or analytics. It is moving into physical execution: coordinating machines, adapting to real‑world variability, and working alongside people on the factory floor. Robotics, autonomous systems, and AI agents must now perceive, reason, and act in dynamic environments.

This transition exposes a critical gap. Traditional automation excels at repetition but struggles with adaptability. Human workers bring judgment and context but are constrained by scale. Physical AI closes that gap by enabling human‑led, AI‑operated systems, where people set intent and intelligent systems execute, learn, and improve over time. Humans are essential for scaled success.

Microsoft and NVIDIA: Accelerating physical AI at scale

Physical AI cannot be delivered through point solutions. It requires agentic-driven, enterprise-grade development, deployment, and operations toolchains and workflows that connect simulation, data, AI models, robotics, and governance into a coherent system.

NVIDIA is building the AI infrastructure that makes physical AI possible, including accelerated computing, open models, simulation libraries, and robotics frameworks and blueprints that enable the ecosystem to build autonomous robotics systems that can perceive, reason, plan, and take action in the physical world. Microsoft complements this with a cloud and data platform designed to operate physical AI securely, at scale, and across the enterprise.

Together, Microsoft and NVIDIA are enabling manufacturers to move beyond pilots toward production‑ready physical AI systems that can be developed, tested, deployed, and continuously improved across heterogeneous environments spanning the product lifecycle, factory operations, and supply chain.

From intelligence to action: Human-agent teams in the factory

At the industrial frontier, AI is not a standalone system, but a digital teammate.

When AI agents are grounded in the proper operational data, embedded in human workflows, and governed end to end, they can assist with tasks such as:

  • Optimizing production lines in real time
  • Coordinating maintenance and quality decisions
  • Adapting operations to supply or demand disruptions
  • Accelerating engineering and product lifecycle decisions

For example, manufacturers are beginning to use simulation‑grounded AI agents to evaluate production changes virtually before deploying them on the factory floor, reducing risk while accelerating decision‑making.

Crucially, frontier manufacturers design these systems so humans remain in control. AI executes, monitors, and recommends, while people provide intent, oversight, and judgment. This balance allows organizations to move faster without losing confidence or control.

The role of trust in scaling physical AI

As physical AI systems scale, trust becomes the limiting factor.

Manufacturers must ensure that AI systems are secure, observable, and operating within policy, especially when they influence safety‑critical or mission‑critical processes. Governance cannot be an afterthought; It must be engineered into the platform itself.

This is why frontier manufacturers treat trust as a first‑class requirement, pairing innovation with visibility, compliance, and accountability. Only then can physical AI move from promising demonstrations to enterprise‑wide deployment.

Why this moment matters—and what’s next

The convergence of AI agents, robotics, simulation, and real‑time data marks an inflection point for manufacturing. What was once experimental is becoming operational. What was once siloed is becoming connected.

At NVIDIA GTC 2026, Microsoft and NVIDIA will demonstrate how this collaboration supports physical AI systems that manufacturers can deploy today and scale responsibly tomorrow. From simulation‑driven development to real‑world execution, the focus is on helping manufacturers cross the industrial frontier with confidence.

For manufacturing leaders, the question is no longer whether physical AI will reshape operations, but how quickly they can adopt it responsibly, at scale, and with trust built in from the start.

Discover more with Microsoft at NVIDIA GTC 2026.

This content was produced by Microsoft. It was not written by MIT Technology Review’s editorial staff.

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This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.

Defense official reveals how AI chatbots could be used for targeting decisions 

The US military might use generative AI systems to rank targets and recommend which to strike first, according to a Defense Department official. 

A list of possible targets could first be fed into a generative AI system that the Pentagon is fielding for classified settings. Humans might then ask the system to analyze the information and prioritize the targets. They would then be responsible for checking and evaluating the results and recommendations. 

OpenAI’s ChatGPT and xAI’s Grok could soon be at the center of exactly these sorts of high-stakes military decisions. Read the full story

—James O’Donnell 

The must-reads 

I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology. 

1 The Pentagon’s CTO claims Claude would “pollute” the defense supply chain 
He blamed a “policy preference” that’s baked into the model. (CNBC
+ Anthropic is reeling from OpenAI’s “compromise” with the DoD. (MIT Technology Review

2 An ex-DOGE staffer has been accused of stealing social security data 
Then taking the information to his new job in the IT division of a government contractor. (Wired
+ He allegedly used a thumb drive to steal the data. (Washington Post

3 Ukraine is offering its battlefield data for AI training 
Allies can access the data to train drones and other UAVs. (Reuters)  
+ Europe has a drone-filled vision for the future of war. (MIT Technology Review)  

4 Meta has postponed its latest AI launch over performance issues 
It fell short of rival models from Google, OpenAI, and Anthropic. (NYT $) 
+ The company’s former AI chief is betting against LLMs. (MIT Technology Review). 

5 X could be breaching sanctions on Iran 
An account for Iran’s new supreme leader may break US rules. (Engadget
+ Hacker group Handala has become the face of Iranian cyberwarfare. (Wired
+ AI is turning the conflict into theater. (MIT Technology Review)  

6 A landmark social media addiction trial is wrapping up 
It’ll decide whether the platforms are liable for harms caused to children. (The Guardian)  
+ AI companions are the next stage of digital addiction. (MIT Technology Review

7 Western AI models have “failed spectacularly” on agriculture in the Global South 
The biggest problem? They’re not trained on local data. (Rest of World

8 Internet outages in Moscow are sparking surging sales of pagers 
The disruptions have been blamed on new tests of web controls. (Bloomberg $) 

9 Why is China obsessed with OpenClaw? 
Lobster-mania is spreading to the general public. (SCMP
Tech-savvy “tinkerers” are cashing in on the craze. (MIT Technology Review

10 Hollywood has soured on Silicon Valley 
Movies and TV shows have swapped eccentric founders for megalomaniac moguls. (NYT $) 

Quote of the day 

“We see a future where intelligence is a utility, like electricity or water, and people buy it from us on a meter.” 

—OpenAI CEO Sam Altman makes a new pitch to investors at a BlackRock event, Gizmodo reports. 

One More Thing 

How the Ukraine-Russia war is reshaping the tech sector in Eastern Europe 

Latvia’s annual national defense exercises took place in September and October, as the Ukraine-Russia war nears its third anniversary.
GATIS INDRēVICS/ LATVIAN MINISTRY OF DEFENSE

When Latvian startup Global Wolf Motors first pitched the idea of a military scooter, it was met with skepticism—and a wall of bureaucracy. Then Russia launched its full-scale invasion of Ukraine in February 2022, and everything changed.  

Suddenly, Ukrainian combat units wanted any equipment they could get their hands on, and they were willing to try out ideas that might not have made the cut in peacetime. 

Within weeks, the scooters were on the front line—and even behind it, being used on daring reconnaissance missions. It signaled that a new product category for companies along Ukraine’s borders had opened: civilian technologies repurposed for military needs. Read the full story

—Peter Guest 

We can still have nice things 

A place for comfort, fun and distraction to brighten up your day. (Got any ideas? Drop me a line.) 

+ A new mini magnet could slash the costs of MRIs and nuclear fusion.  
+ This interactive map of Earth offers new routes to facts about our planet. 
+ Escape the news cycle with this deep dive into the power of fantasy and nature. (Big thanks to reader and MIT alum Vicki for the find!) 
+ Reports of reading’s death are greatly exaggerated

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Human-made glass is thousands of years old. But it’s now poised to find its way into the AI chips used in the world’s newest and largest data centers. This year, a South Korean company called Absolics is planning to start commercial production of special glass panels designed to make next-generation computing hardware more powerful and energy efficient. Other companies, including Intel, are also pushing forward in this area. If all goes well, such glass technology could reduce the energy demands of the sorts of high-performance computing chips used in AI data centers—and it could eventually do the same for consumer laptops and mobile devices if production costs fall.

The idea is to use glass as the substrate, or layer, on which multiple silicon chips are connected. This form of “packaging” is an increasingly popular way to build computing hardware, because it lets engineers combine specialized chips designed for specific functions into a single system. But it presents challenges, including the fact that hardworking chips can run so hot they physically warp the substrate they’re built on. This can lead to misaligned components and may reduce how efficiently the chips can be cooled, leading to damage or premature failure. 

“As AI workloads surge and package sizes expand, the industry is confronting very real mechanical constraints that impact the trajectory of high-performance computing,” says Deepak Kulkarni, a senior fellow at the chip design company Advanced Micro Devices (AMD). “One of the most fundamental is warpage.”

That’s where glass comes in. It can handle the added heat better than existing substrates, and it will let engineers keep shrinking chip packages—which will make them faster and more energy efficient. It “unlocks the ability to keep scaling package footprints without hitting a mechanical wall,” says Kulkarni. 

Momentum is building behind the shift. Absolics has finished building a factory in the US that is dedicated to producing glass substrates for advanced chips and expects to begin commercial manufacturing this year. The US semiconductor manufacturer Intel is working toward incorporating glass in its next-generation chip packages, and its research has spurred other companies in the chip packaging supply chain to invest in it as well. South Korean and Chinese companies are among the early adopters. “Historically, this is not the first attempt to adopt glass in semiconductor packaging,” says Bilal Hachemi, senior technology and market analyst at the market research firm Yole Group. “But this time, the ecosystem is more solid and wider; the need for glass-based [technology] is sharper.” 

Fragile but mighty

Chip packaging has relied on organic substrates such as fiberglass-reinforced epoxy since the 1990s, says Rahul Manepalli, vice president of advanced packaging at Intel. But electrochemical complications limit how closely designers can place drilled holes to create copper-coated signal and power connections between the chips and the rest of the system. Chip designers must also account for the unpredictable shrinkage and distortion that organic substrates undergo as chips heat up and cool down. “We realized about a decade ago that we are going to have some limitations with organic substrates,” says Manepalli.

close up on a grid of glass substrate test units held by a gloved hand
These glass substrate test units were photographed at an Intel facility in Chandler, Arizona, in 2023.
INTEL CORPORATION

Glass may help overcome a lot of these limitations. Its thermal stability could allow engineers to create 10 times more connections per millimeter than organic substrates, says Manepalli. With denser connections, Intel’s designers can then stuff 50% more silicon chips into the same package area, improving computational capability. The denser connections also enable more efficient routing for the copper wires that deliver power to the chip. And the fact that glass dissipates heat more efficiently allows for chip designs that reduce overall power consumption. 

“The benefits of glass core substrates are undeniable,” says Manepalli. “It’s clear that the benefits will drive the industry to make this happen sooner rather than later, and we want to be one of the first ones who do it.” 

However, working with glass creates its own challenges. For one thing, it’s fragile. Glass substrates for data center chip packages are made from panels that are only about 700 micrometers to 1.4 millimeters thick, which leaves them susceptible to cracking or even shattering, says Manepalli. Researchers at Intel and other organizations have spent years figuring out how to use other materials and special tools to integrate the glass panels safely into semiconductor manufacturing processes. 

Now, Manepalli says, Intel’s research and development teams are reliably fabricating glass panels and churning out test chip packages that incorporate glass—and in early 2025 they demonstrated that a functional device with a glass core substrate could boot up the Windows operating system. It’s a significant improvement from the early testing days, when hundreds of glass panels got cracked every couple of days, he says.

Semiconductor manufacturers already use glass for more limited purposes, such as temporary support structures for silicon wafers. But the independent market research firm IDTechEx estimates there’s a big market for glass substrates, one that could boost the semiconductor market for glass from $1 billion in 2025 to as much as $4.4 billion by 2036. 

The material could have additional benefits if it takes off. Glass can be made astoundingly smooth—5,000 times smoother than organic substrates. This would eliminate defects that can arise as metal gets layered onto semiconductors, says Xiaoxi He, a research analyst at IDTechEx. Defects in these layers can worsen chips’ performance or even render them unusable.  

Glass could also help speed the movement of data. The material can guide light, which means chip designers could use it to build high-speed signal pathways directly into the substrate. Glass “holds enormous potential for the future of energy-efficient AI compute,” says Kulkarni at AMD, because a light-based system could move signals around with far less energy than the “power-hungry” copper pathways that are currently used to carry signals between chips in a package.

A panel pivot

Early research on glass packaging started at the 3D Systems Packaging Research Center at the Georgia Institute of Technology in 2009. The university eventually partnered with Absolics, a subsidiary of SKC, a South Korean company that produces chemicals and advanced materials. SKC constructed a semiconductor facility for manufacturing glass substrates in Covington, Georgia, in 2024, and the glass substrate partnership between Absolics and Georgia Tech was eventually awarded two grants in the same year—worth a combined $175 million—throughthe US government’s CHIPS for America program, established under the administration of President Joe Biden.

""
An Absolics employee monitors production of an early version of the company’s glass substrate.
COURTESY OF ABSOLICS INC

Now Absolics is moving toward commercialization; it plans to start manufacturing small quantities of glass substrates for customers this year. The company has led the way in commercializing glass substrates, says Yongwon Lee, a research engineer at Georgia Tech who is not directly involved in the commercial partnership with Absolics.

Absolics says its facility can currently produce a maximum of 12,000 square meters of glass panels a year. That’s enough, Lee estimates, to provide glass substrates for between 2 million and 3 million chip packages the size of Nvidia’s H100 GPU.

But the company isn’t alone. Lee says that multiple large manufacturers, including Samsung Electronics, Samsung Electro-Mechanics, and LG Innotek, have “significantly accelerated” their research and pilot production efforts in glass packaging over the past year. “This trend suggests that the glass substrate ecosystem is evolving from a single early mover to a broader industrial race,” he says.

Other companies are pivoting to play more specialized roles in the glass substrate supply chain. In 2025, JNTC, a company that makes electrical connectors and tempered glass for electronics, established a facility in South Korea that’s capable of producing 10,000 semi-finished glass panels per month. Such panels include drilled holes for vertical electrical connections and thin metal layers coating the glass, but they require additional manufacturing work for installation in chip packages. 

Last year, that South Korean facility began taking orders to supply semi-finished glass to both specialized substrate companies and semiconductor manufacturers. The company plans to expand the facility’s production in 2026 and open an additional manufacturing line in Vietnam in 2027.  Such industry actions show how quickly glass substrate technology is moving from prototype to commercialization—and how many tech players are betting that glass could be a surprisingly strong foundation for the future of computing and AI.

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GTC — which stands for GPU Technology Conference — is Nvidia’s flagship annual event, where the chipmaker typically uses the spotlight to announce new products, champion partnerships, and lay out its vision for the future of computing. Huang’s keynote will focus on Nvidia’s role in the future of computing and AI.
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